| Played in San Jose, CA, weather: 52 degrees, fair, 3 mph wind. |
| San Francisco won the toss and elected to receive. |
| Start of first quarter. |
| (1Q: 15:00) Van Jennings kicked off 67 yards from the IND30. Keith Lewis returned the ball 26 yards to the SFO29. Tackled by Donovan Frassrand. PENALTY: San Francisco was called for Holding on the Kick Return. |
| 1-10-SFO09 (1Q: 14:37) Alex Smith pass completed to WR Mickey Mesa for 18 yards. Tackled by DT Anthony McFarland. Mesa gained 7 yards after the catch. |
| 1-10-SFO27 (1Q: 13:59) Ahmad Bradshaw ran around the left tackle for 9 yards. Tackled by DT Quinn Pitcock, assisted by CB Leigh Bodden. Key block delivered by Joe Berger. Berger flattened Robert Mathis to ensure the play's success. |
| 2-1-SFO36 (1Q: 13:35) Ahmad Bradshaw ran inside the left guard for -1 yards. Tackled by ILB Gary Brackett. |
| 3-2-SFO35 (1Q: 12:48) Alex Smith pass completed to WR Harvey Woodard for 9 yards. Tackled by CB Billy McNeil. Woodard gained 1 yard after the catch. The quarterback threw away from the double coverage. |
| 1-10-SFO44 (1Q: 12:08) Emmanuel McGregor ran around right end for 1 yard. Tackled by S Bob Sanders, assisted by DT J.J. Solik. PENALTY: Indianapolis was called for Too Many Men on the Field. |
| 1-5-SFO49 (1Q: 11:59) Emmanuel McGregor ran around the left tackle for 1 yard. Tackled by DT Jimmy Kennedy. |
| 2-4-SFO50 (1Q: 11:19) Emmanuel McGregor ran around right end for 0 yards. Tackled by ILB Gary Brackett. |
| 3-4-SFO50 (1Q: 10:32) Alex Smith pass completed to WR Troy Williamson for 6 yards. Tackled by CB Ricky Manning Jr., assisted by CB Bart Crawford. Williamson gained 1 yard after the catch. The quarterback threw into double coverage. |
| 1-10-IND44 (1Q: 10:02) Emmanuel McGregor ran around the left tackle for 4 yards. Tackled by CB Ricky Manning Jr., assisted by ILB Gary Brackett. |
| 2-6-IND40 (1Q: 09:27) Alex Smith sacked by DE Dwight Freeney for a loss of 7 yards. Freeney ran right past Adam Snyder and knocked down the quarterback. |
| 3-13-IND47 (1Q: 08:57) Alex Smith pass completed to WR Mickey Mesa for 21 yards. Tackled by S Bob Sanders. Mesa gained 1 yard after the catch. The quarterback threw away from the double coverage. |
| 1-10-IND26 (1Q: 08:28) Alex Smith pass completed to RB Emmanuel McGregor for 6 yards. Tackled by DE Dwight Freeney, assisted by ILB Gary Brackett. McGregor gained 6 yards after the catch. |
| 2-4-IND20 (1Q: 07:54) Alex Smith pass completed to WR Mickey Mesa for 6 yards. Tackled by S Bob Sanders. Mesa gained 2 yards after the catch. |
| 1-10-IND14 (1Q: 07:07) Ahmad Bradshaw ran inside the right guard for -1 yards. Tackled by DT Jimmy Kennedy, assisted by S Bob Sanders. |
| 2-11-IND15 (1Q: 06:38) Alex Smith pass completed to WR Darrell Jackson for 15 yards and a TOUCHDOWN! Jackson gained 5 yards after the catch. The quarterback threw away from the double coverage. San Francisco 6, Indianapolis 0 |
| (1Q: 06:38) Extra point by Lawrence Tynes was good. San Francisco 7, Indianapolis 0 |
| (1Q: 06:32) Lawrence Tynes kicked off 78 yards from the SFO30. Touchback. |
| 1-10-IND20 (1Q: 06:32) Joseph Addai ran around left end for 1 yard. Tackled by OLB Steve Humphrey, assisted by DE Jim Ellison. |
| 2-9-IND21 (1Q: 06:06) Peyton Manning pass completed to FB Leonard Weaver for 2 yards. Tackled by CB Shawntae Spencer. |
| 3-7-IND23 (1Q: 05:31) Peyton Manning pass completed to WR Anthony Gonzalez for 18 yards. Tackled by CB Marcus Hudson, assisted by S Sean Taylor. |
| 1-10-IND41 (1Q: 05:07) Peyton Manning pass completed to WR Steve Smith for 36 yards. The receiver went out of bounds. Tackled by OLB Tracy White. Smith gained 11 yards after the catch. |
| 1-10-SFO23 (1Q: 04:30) Peyton Manning pass completed to WR Steve Smith for 13 yards. Tackled by OLB Tracy White. The receiver ran his route right over the middle of the field. Smith gained 2 yards after the catch. |
| 1-10-SFO10 (1Q: 03:58) Joseph Addai ran inside the left guard for 9 yards. Tackled by OLB Steve Humphrey. Key block delivered by Ryan Lilja. |
| 2-1-SFO01 (1Q: 03:17) Peyton Manning pass was dropped by WR Reggie Wayne. |
| 3-1-SFO01 (1Q: 03:11) Joseph Addai ran around left end for 0 yards. Tackled by DT Chris Hoke, assisted by ILB Patrick Willis. |
| 4-1-SFO01 (1Q: 02:45) Van Jennings attempted a 18 yard field goal and succeeded. San Francisco 7, Indianapolis 3 |
| (1Q: 02:40) Van Jennings kicked off 61 yards from the IND30. Mickey Mesa returned the ball 20 yards to the SFO29. Tackled by Leonard Weaver. |
| 1-10-SFO29 (1Q: 02:10) Ahmad Bradshaw ran inside the left guard for 14 yards. Tackled by ILB Gary Brackett, assisted by CB Bart Crawford. Key block delivered by Adam Snyder. |
| 1-10-SFO43 (1Q: 01:44) Emmanuel McGregor ran inside the right guard for 3 yards. Tackled by ILB Gary Brackett, assisted by DE Dwight Freeney. |
| 2-7-SFO46 (1Q: 01:05) Alex Smith pass completed to RB Emmanuel McGregor for 9 yards. Tackled by CB Bart Crawford, assisted by CB Billy McNeil. |
| 1-10-IND45 (1Q: 00:24) Alex Smith pass completed to RB Emmanuel McGregor for 6 yards. Tackled by OLB Willie Cesario. The receiver ran his route right over the middle of the field. |
| Start of second quarter. |
| 2-4-IND39 (2Q: 15:00) Ahmad Bradshaw ran around the left tackle for -1 yards. Tackled by ILB Gary Brackett, assisted by CB Ricky Manning Jr.. |
| 3-5-IND40 (2Q: 14:14) Alex Smith pass completed to WR Arnaz Battle for 5 yards. Tackled by OLB Freddie Keiaho. Battle gained 7 yards after the catch. The quarterback threw away from the double coverage. PENALTY: Indianapolis was called for Offsides. The penalty was declined. |
| 1-10-IND35 (2Q: 14:08) Ahmad Bradshaw ran inside the right guard for 0 yards. Tackled by DE Dwight Freeney. |
| 2-10-IND35 (2Q: 13:35) Emmanuel McGregor ran inside the left guard for 8 yards. Tackled by DE Robert Mathis. Key block delivered by Tre' Stallings. |
| 3-2-IND27 (2Q: 12:57) Emmanuel McGregor ran around the left tackle for 4 yards. Tackled by CB Ricky Manning Jr.. Key block delivered by Devin Schwartz. |
| 1-10-IND23 (2Q: 12:29) Alex Smith pass fell incomplete, intended for RB Emmanuel McGregor. DE Dwight Freeney defended the pass. |
| 2-10-IND23 (2Q: 12:25) Emmanuel McGregor ran around left end for 1 yard. Tackled by CB Leigh Bodden, assisted by S Lamar Cox. |
| 3-9-IND22 (2Q: 11:55) Alex Smith pass completed to TE Devin Schwartz for 21 yards. Tackled by S Lamar Cox. The receiver ran his route right over the middle of the field. Schwartz gained 11 yards after the catch. The quarterback threw away from the double coverage. |
| 1-1-IND01 (2Q: 11:25) Ahmad Bradshaw ran outside the right tackle for -1 yards. Tackled by CB Billy McNeil. |
| 2-2-IND02 (2Q: 10:50) Emmanuel McGregor ran around left end for 1 yard. Tackled by DE Robert Mathis. |
| 3-1-IND01 (2Q: 10:26) Ahmad Bradshaw ran a counterplay inside the left tackle for 1 yard and a TOUCHDOWN! Key block delivered by Justin Smiley. San Francisco 13, Indianapolis 3 |
| (2Q: 10:26) Extra point by Lawrence Tynes was good. San Francisco 14, Indianapolis 3 |
| (2Q: 10:18) Lawrence Tynes kicked off 65 yards from the SFO30. Will Borders returned the ball 37 yards to the IND42. Tackled by Vernon Davis. |
| 1-10-IND42 (2Q: 09:42) Joseph Addai ran inside the right guard for 2 yards. Tackled by DE Jim Ellison, assisted by S Sean Taylor. |
| 2-8-IND44 (2Q: 09:13) Peyton Manning pass fell incomplete, intended for WR Steve Smith. DT Jonathan Babineaux hurried the quarterback into a bad throw. The quarterback threw into double coverage. |
| 3-8-IND44 (2Q: 09:01) Peyton Manning pass completed to WR Steve Smith for 21 yards. Tackled by CB Daymeion Hughes. The receiver ran his route right over the middle of the field. Smith gained 6 yards after the catch. |
| 1-10-SFO35 (2Q: 08:40) Peyton Manning pass was blocked at the line, intended for WR Anthony Gonzalez. OLB Tully Banta-Cain blocked the pass. The quarterback threw away from the double coverage. PENALTY: San Francisco was called for Defensive Holding. |
| 1-10-SFO30 (2Q: 08:34) Peyton Manning pass fell incomplete, intended for WR Steve Smith. OLB Steve Humphrey hurried the quarterback into a bad throw. |
| 2-10-SFO30 (2Q: 08:23) Peyton Manning pass fell incomplete, intended for WR Wendell Burgess. DE Levon Dole hurried the quarterback into a bad throw. |
| 3-10-SFO30 (2Q: 08:13) Peyton Manning pass fell incomplete, intended for WR Steve Smith. CB Daymeion Hughes defended the pass. The quarterback threw into double coverage. |
| 4-10-SFO30 (2Q: 08:07) Van Jennings attempted a 47 yard field goal and succeeded. San Francisco 14, Indianapolis 6 |
| (2Q: 08:02) Van Jennings kicked off 58 yards from the IND30. Mickey Mesa returned the ball 20 yards to the SFO32. Tackled by Will Borders. |
| 1-10-SFO32 (2Q: 07:43) Emmanuel McGregor ran around right end for 4 yards. Tackled by OLB Willie Cesario. |
| 2-6-SFO36 (2Q: 07:07) Alex Smith pass fell incomplete, intended for TE Vernon Davis. DE Dwight Freeney hurried the quarterback into a bad throw. The quarterback threw away from the double coverage. |
| 3-6-SFO36 (2Q: 06:58) Alex Smith pass fell incomplete, intended for RB Emmanuel McGregor. S Lamar Cox defended the pass. The quarterback threw away from the double coverage. |
| 4-6-SFO36 (2Q: 06:53) Bryant Lyle punted 34 yards. Lamar Cox returned the kick -3 yards to the IND27. Tackled by Darrell Jackson. |
| 1-10-IND27 (2Q: 06:42) Joseph Addai ran inside the left tackle for 5 yards. Tackled by S K.C. Sullivan. Key block delivered by Bob Craig. |
| 2-5-IND32 (2Q: 06:06) Joseph Addai ran outside the right tackle for 1 yard. Tackled by S K.C. Sullivan. |
| 3-4-IND33 (2Q: 05:20) Peyton Manning pass completed to RB Donovan Frassrand for 3 yards. Tackled by ILB Patrick Willis. The quarterback threw away from the double coverage. |
| 4-1-IND36 (2Q: 04:44) Perry Malone punted 51 yards. Antoine Santulli returned the kick 13 yards to the SFO26. Tackled by Will Borders. San Francisco's Devin Schwartz was hurt on the play. This appears to be a minor hand injury. He should be able to remain in the game. |
| 1-10-SFO26 (2Q: 04:34) Emmanuel McGregor ran inside the left guard for 8 yards. Tackled by DT Quinn Pitcock, assisted by S Bob Sanders. Key block delivered by Joe Staley. |
| 2-2-SFO34 (2Q: 03:55) Emmanuel McGregor ran around right end for 3 yards. Tackled by OLB Willie Cesario. Key block delivered by James Harper. PENALTY: Indianapolis was called for Offsides. |
| 1-10-SFO39 (2Q: 03:48) Alex Smith pass was thrown incomplete, intended for WR Harvey Woodard. |
| 2-10-SFO39 (2Q: 03:37) Alex Smith pass fell incomplete, intended for FB Geoff Goodwin. ILB Gary Brackett defended the pass. |
| 3-10-SFO39 (2Q: 03:32) Alex Smith pass fell incomplete, intended for TE Devin Schwartz. DE Robert Mathis hurried the quarterback into a bad throw. |
| 4-10-SFO39 (2Q: 03:26) Bryant Lyle punted 51 yards. Lamar Cox returned the kick -3 yards to the IND07. Tackled by Darrell Jackson. |
| 1-10-IND07 (2Q: 03:18) Peyton Manning pass was blocked at the line, intended for WR Wendell Burgess. OLB Steve Humphrey blocked the pass. The quarterback threw away from the double coverage. |
| 2-10-IND07 (2Q: 03:09) Donovan Frassrand ran inside the right tackle for 2 yards. Tackled by S K.C. Sullivan. PENALTY: Indianapolis was called for Offensive Holding. |
| 2-13-IND04 (2Q: 03:03) Joseph Addai ran around the left tackle for 4 yards. Tackled by OLB Tully Banta-Cain, assisted by S Sean Taylor. |
| 3-9-IND08 (2Q: 02:21) Peyton Manning pass fell incomplete, intended for RB Joseph Addai. ILB Patrick Willis defended the pass. PENALTY: San Francisco was called for Illegal Contact. |
| 1-10-IND13 (2Q: 02:15) Peyton Manning pass completed to TE Ben Utecht for 9 yards. The receiver went out of bounds. Tackled by S Mike Doss, assisted by CB Marcus Hudson. |
| Official time out for the two-minute warning. |
| 2-1-IND22 (2Q: 02:00) Peyton Manning pass fell incomplete, intended for WR Anthony Gonzalez. ILB Norm Bronson defended the pass. |
| 3-1-IND22 (2Q: 01:50) Donovan Frassrand ran inside the left tackle for 2 yards. Tackled by ILB Patrick Willis. Key block delivered by Andrew Carnahan. |
| 1-10-IND24 (2Q: 01:18) Peyton Manning pass was blocked at the line, intended for WR Wendell Burgess. S Mike Doss blocked the pass. |
| 2-10-IND24 (2Q: 01:09) Peyton Manning pass completed to RB Joseph Addai for 6 yards. Tackled by CB Daymeion Hughes, assisted by ILB Patrick Willis. The quarterback threw away from the double coverage. |
| 3-4-IND30 (2Q: 00:47) Peyton Manning pass fell incomplete, intended for WR Anthony Gonzalez. DE Levon Dole drove right through Dylan Gandy to hurry the quarterback. The quarterback threw away from the double coverage. |
| 4-4-IND30 (2Q: 00:38) Perry Malone punted 55 yards. Antoine Santulli returned the kick 20 yards to the SFO35. Tackled by Ryan Diem. |
| 1-10-SFO35 (2Q: 00:28) Emmanuel McGregor ran around the left tackle for 10 yards. Tackled by S Bob Sanders. Key block delivered by Tre' Stallings. |
| Start of third quarter. |
| (3Q: 15:00) Lawrence Tynes kicked off 64 yards from the SFO30. Bryant Johnson returned the ball 30 yards to the IND36. Tackled by K.C. Sullivan. PENALTY: Indianapolis was called for an Illegal Block on the Kick Return. |
| 1-10-IND15 (3Q: 14:26) Peyton Manning pass was blocked at the line, intended for WR Steve Smith. OLB Steve Humphrey blocked the pass. PENALTY: San Francisco was called for Offsides. |
| 1-5-IND20 (3Q: 14:18) Peyton Manning pass completed to WR Steve Smith for 31 yards. Tackled by OLB Tracy White. Smith gained 11 yards after the catch. |
| 1-10-SFO49 (3Q: 13:49) Peyton Manning pass fell incomplete, intended for WR Reggie Wayne. ILB Patrick Willis defended the pass. |
| 2-10-SFO49 (3Q: 13:42) Peyton Manning pass completed to RB Joseph Addai for 6 yards. Tackled by S Sean Taylor, assisted by CB Shawntae Spencer. Addai gained 1 yard after the catch. The quarterback threw away from the double coverage. |
| 3-4-SFO43 (3Q: 12:59) Peyton Manning pass fell incomplete, intended for WR Steve Smith. S Sean Taylor defended the pass. The quarterback threw away from the double coverage. |
| 4-4-SFO43 (3Q: 12:52) Perry Malone punted 40 yards. The ball was downed at the SFO03. |
| 1-10-SFO03 (3Q: 12:45) Ahmad Bradshaw ran around the left tackle for -1 yards. Tackled by S Lamar Cox. |
| 2-11-SFO02 (3Q: 11:58) Emmanuel McGregor ran inside the right guard for 4 yards. Tackled by CB Leigh Bodden. |
| 3-7-SFO06 (3Q: 11:17) Alex Smith pass completed to WR Harvey Woodard for 17 yards. Tackled by OLB Freddie Keiaho. Woodard gained 12 yards after the catch. The quarterback threw into double coverage. |
| 1-10-SFO23 (3Q: 10:39) Alex Smith pass completed to RB Emmanuel McGregor for 8 yards. Tackled by ILB Gary Brackett. The quarterback threw away from the double coverage. |
| 2-2-SFO31 (3Q: 09:55) Emmanuel McGregor ran inside the left guard for 1 yard. Tackled by OLB Willie Cesario, assisted by OLB Freddie Keiaho. |
| 3-1-SFO32 (3Q: 09:20) Alex Smith pass completed to WR Harvey Woodard for 12 yards. Tackled by ILB Gary Brackett. Woodard gained 5 yards after the catch. |
| 1-10-SFO44 (3Q: 08:52) Emmanuel McGregor ran inside the right guard for 3 yards. Tackled by DT Quinn Pitcock, assisted by S Bob Sanders. |
| 2-7-SFO47 (3Q: 08:23) Emmanuel McGregor ran inside the right guard for 1 yard. Tackled by ILB Gary Brackett, assisted by S Bob Sanders. |
| 3-6-SFO48 (3Q: 08:01) Alex Smith pass completed to WR Darrell Jackson for 12 yards. Tackled by CB Ricky Manning Jr., assisted by OLB Willie Cesario. PENALTY: San Francisco was called for Offensive Holding. |
| 3-16-SFO38 (3Q: 07:54) Emmanuel McGregor ran around right end for 10 yards. Tackled by CB Billy McNeil, assisted by OLB Willie Cesario. |
| 4-6-SFO48 (3Q: 07:25) Bryant Lyle punted 52 yards. Touchback. |
| 1-10-IND20 (3Q: 07:18) Peyton Manning pass fell incomplete, intended for WR Steve Smith. S Mike Doss defended the pass. |
| 2-10-IND20 (3Q: 07:11) Peyton Manning pass completed to WR Steve Smith for 11 yards. Tackled by S Sean Taylor. Smith gained 5 yards after the catch. |
| 1-10-IND31 (3Q: 06:38) Joseph Addai ran outside the right tackle for 3 yards. Tackled by DT Jonathan Babineaux, assisted by S Mike Doss. |
| 2-7-IND34 (3Q: 06:14) Joseph Addai ran inside the right guard for 1 yard. Tackled by DT Jonathan Babineaux. |
| 3-6-IND35 (3Q: 05:27) Peyton Manning sacked by OLB Steve Humphrey for a loss of 8 yards. Sack allowed by Ryan Lilja. |
| 4-14-IND27 (3Q: 04:48) Perry Malone punted 38 yards. Antoine Santulli called for a fair catch at the SFO35. |
| 1-10-SFO35 (3Q: 04:37) Alex Smith pass completed to RB Emmanuel McGregor for 4 yards. Tackled by OLB Freddie Keiaho, assisted by S Bob Sanders. McGregor gained 1 yard after the catch. |
| 2-6-SFO39 (3Q: 03:56) Alex Smith pass fell incomplete, intended for WR Arnaz Battle. DT Jimmy Kennedy hurried the quarterback into a bad throw. The quarterback threw into double coverage. |
| 3-6-SFO39 (3Q: 03:50) Alex Smith sacked by DE Robert Mathis and DT Quinn Pitcock for a loss of 6 yards. Sack allowed by Joe Staley. |
| 4-12-SFO33 (3Q: 03:26) Bryant Lyle punted 65 yards. The ball was marked out of bounds at the IND02. PENALTY: Indianapolis was called for Roughing the Kicker. |
| 1-10-SFO48 (3Q: 03:17) Emmanuel McGregor ran inside the left tackle for 6 yards. Tackled by ILB Gary Brackett, assisted by CB Bart Crawford. Key block delivered by Tre' Stallings. |
| 2-4-IND46 (3Q: 02:39) Emmanuel McGregor ran around the left tackle for 2 yards. Tackled by ILB Gary Brackett, assisted by DT Quinn Pitcock. |
| 3-2-IND44 (3Q: 01:56) Alex Smith pass fell incomplete, intended for WR Darrell Jackson. CB Bart Crawford defended the pass. The quarterback threw away from the double coverage. |
| 4-2-IND44 (3Q: 01:52) Bryant Lyle punted 44 yards. Touchback. |
| 1-10-IND20 (3Q: 01:47) Peyton Manning pass completed to WR Steve Smith for 15 yards. Tackled by CB Daymeion Hughes. The receiver ran his route right over the middle of the field. PENALTY: San Francisco was called for Offsides. The penalty was declined. |
| 1-10-IND35 (3Q: 01:39) Peyton Manning pass fell incomplete, intended for WR Steve Smith. OLB Steve Humphrey defended the pass. The defense looked very familiar with that play. The quarterback threw into double coverage. PENALTY: San Francisco was called for Offsides. |
| 1-5-IND40 (3Q: 01:30) Peyton Manning pass fell incomplete, intended for RB Donovan Frassrand. CB Marcus Hudson defended the pass. |
| 2-5-IND40 (3Q: 01:20) Peyton Manning pass fell incomplete, intended for WR Steve Smith. DE Levon Dole simply tossed Bob Craig aside to reach the quarterback and hurry the throw. The quarterback threw into double coverage. |
| 3-5-IND40 (3Q: 01:14) Peyton Manning pass completed to WR Will Borders for 5 yards. Tackled by S Mike Doss, assisted by CB Marcus Hudson. |
| 1-10-IND45 (3Q: 00:29) Joseph Addai ran inside the right guard for 3 yards. Tackled by ILB Patrick Willis. |
| 2-7-IND48 (3Q: 00:01) Donovan Frassrand ran inside the left tackle for 4 yards. Tackled by S Sean Taylor. |
| Start of fourth quarter. |
| 3-3-SFO48 (4Q: 15:00) Peyton Manning pass completed to WR Reggie Wayne for 2 yards. Tackled by CB Daymeion Hughes. The quarterback threw into double coverage. |
| 4-1-SFO46 (4Q: 14:20) Perry Malone punted 46 yards. Touchback. |
| 1-10-SFO20 (4Q: 14:15) Emmanuel McGregor ran inside the right tackle for 11 yards. Tackled by CB Bart Crawford. Key block delivered by Adam Snyder. |
| 1-10-SFO31 (4Q: 13:51) Alex Smith pass completed to RB Emmanuel McGregor for 1 yard. Tackled by OLB Freddie Keiaho. The quarterback threw away from the double coverage. |
| 2-9-SFO32 (4Q: 13:10) Emmanuel McGregor ran outside the right tackle for 7 yards. Tackled by ILB Gary Brackett. |
| 3-2-SFO39 (4Q: 12:36) Alex Smith scrambled for 5 yards. Tackled by S Bob Sanders. |
| 1-10-SFO44 (4Q: 12:08) Alex Smith pass fell incomplete, intended for WR Arnaz Battle. DE Robert Mathis hurried the quarterback into a bad throw. The defense looked very familiar with that play. The quarterback threw away from the double coverage. |
| 2-10-SFO44 (4Q: 12:05) Alex Smith pass fell incomplete, intended for WR Harvey Woodard. OLB Willie Cesario defended the pass. |
| 3-10-SFO44 (4Q: 12:02) Alex Smith pass completed to WR Darrell Jackson for 12 yards. Tackled by CB Billy McNeil. |
| 1-10-IND44 (4Q: 11:32) Emmanuel McGregor ran inside the right tackle for 1 yard. Tackled by DT Jimmy Kennedy. |
| 2-9-IND43 (4Q: 10:57) Alex Smith pass completed to WR Arnaz Battle for 27 yards. Tackled by ILB Gary Brackett. The receiver ran his route right over the middle of the field. Battle gained 9 yards after the catch. |
| 1-10-IND16 (4Q: 10:14) Alex Smith sacked by OLB Willie Cesario for a loss of 6 yards. Sack allowed by Adam Snyder. |
| 2-16-IND22 (4Q: 09:48) Ahmad Bradshaw ran inside the left guard for 10 yards. Tackled by CB Bart Crawford. |
| 3-6-IND12 (4Q: 09:22) Alex Smith pass completed to WR Arnaz Battle for 12 yards and a TOUCHDOWN! San Francisco 20, Indianapolis 6 |
| (4Q: 09:22) Extra point by Lawrence Tynes was good. San Francisco 21, Indianapolis 6 |
| (4Q: 09:12) Lawrence Tynes kicked off 60 yards from the SFO30. Bryant Johnson returned the ball 23 yards to the IND33. Tackled by Tully Banta-Cain. |
| 1-10-IND33 (4Q: 08:41) Donovan Frassrand ran around the left tackle for 2 yards. Tackled by ILB Patrick Willis. ILB Jamar Williams knocked down Dominic Russell to break up the play. |
| 2-8-IND35 (4Q: 07:57) Peyton Manning pass was intended for WR Reggie Wayne and was intercepted by OLB Steve Humphrey at the IND49. Tackled by Reggie Wayne. |
| 1-10-IND49 (4Q: 07:46) Emmanuel McGregor ran around left end for 3 yards. Tackled by DT Quinn Pitcock, assisted by OLB Willie Cesario. PENALTY: Indianapolis was called for an Intentional Face Mask. |
| 1-10-IND31 (4Q: 07:39) Emmanuel McGregor ran around left end for 31 yards and a TOUCHDOWN! Key block delivered by Joe Berger. Berger ran over Gary Brackett to set up the play. San Francisco 27, Indianapolis 6 |
| (4Q: 07:39) Extra point by Lawrence Tynes was good. San Francisco 28, Indianapolis 6 |
| (4Q: 07:24) Lawrence Tynes kicked off 58 yards from the SFO30. Will Borders returned the ball 40 yards to the SFO48. Tackled by Darrell Jackson. PENALTY: Indianapolis was called for Holding on the Kick Return. |
| 1-10-IND32 (4Q: 07:01) Peyton Manning pass fell incomplete, intended for WR Steve Smith. CB Shawntae Spencer defended the pass. The quarterback threw into double coverage. |
| 2-10-IND32 (4Q: 06:53) Peyton Manning pass completed to RB Joseph Addai for 9 yards. Tackled by DE Levon Dole. Addai gained 2 yards after the catch. The quarterback threw away from the double coverage. |
| 3-1-IND41 (4Q: 06:32) PENALTY: Indianapolis was called for a False Start. |
| 3-6-IND36 (4Q: 06:19) Peyton Manning sacked by DE Levon Dole for a loss of 6 yards. Dole ran right past Dominic Russell and knocked down the quarterback. |
| 4-12-IND30 (4Q: 05:57) Peyton Manning pass fell incomplete, intended for WR Anthony Gonzalez. DE Jim Ellison simply tossed Ryan Lilja aside to reach the quarterback and hurry the throw. The quarterback threw into double coverage. The ball goes over on downs. |
| 1-10-IND30 (4Q: 05:51) Emmanuel McGregor ran inside the right guard for 3 yards. Tackled by S Lamar Cox. |
| 2-7-IND27 (4Q: 05:06) Ahmad Bradshaw ran inside the left guard for 1 yard. Tackled by CB Bart Crawford. |
| 3-6-IND26 (4Q: 04:22) Emmanuel McGregor ran around right end for 12 yards. Tackled by DT Quinn Pitcock. Key block delivered by James Harper. |
| 1-10-IND14 (4Q: 03:35) Emmanuel McGregor ran outside the right tackle for 1 yard. Tackled by S Bob Sanders, assisted by OLB Willie Cesario. |
| 2-9-IND13 (4Q: 02:48) Emmanuel McGregor ran outside the right tackle for 2 yards. Tackled by S Bob Sanders, assisted by DT J.J. Solik. The ball was fumbled and recovered by SFO Joe Staley to the IND11. |
| Indianapolis called a time out. |
| 3-7-IND11 (4Q: 02:38) Emmanuel McGregor ran inside the left guard for 4 yards. Tackled by DT Quinn Pitcock, assisted by S Bob Sanders. |
| Indianapolis called a time out. |
| 4-3-IND07 (4Q: 02:26) Lawrence Tynes attempted a 24 yard field goal and succeeded. San Francisco 31, Indianapolis 6 |
| (4Q: 02:19) Lawrence Tynes kicked off 65 yards from the SFO30. Bryant Johnson returned the ball 18 yards to the IND23. Tackled by Nate Clements. Indianapolis's Ben Utecht was hurt on the play. |
| 1-10-IND23 (4Q: 02:11) Peyton Manning pass completed to WR Steve Smith for 31 yards. Tackled by OLB Steve Humphrey. The receiver ran his route right over the middle of the field. |
| Official time out for the two-minute warning. |
| 1-10-SFO46 (4Q: 02:00) George Wrighster ran inside the left guard for 1 yard. Tackled by S Sean Taylor, assisted by DT Jonathan Babineaux. |
| 2-9-SFO45 (4Q: 01:22) Peyton Manning pass was blocked at the line, intended for WR Bryant Johnson. S Sean Taylor blocked the pass. |
| 3-9-SFO45 (4Q: 01:12) Peyton Manning pass was blocked at the line, intended for WR Anthony Gonzalez. DT Jonathan Babineaux blocked the pass. |
| 4-9-SFO45 (4Q: 01:04) Peyton Manning scrambled for 10 yards. Tackled by OLB Steve Humphrey and assisted by CB Shawntae Spencer. |
| 1-10-SFO35 (4Q: 00:39) Peyton Manning pass completed to WR Steve Smith for 6 yards. Tackled by CB Shawntae Spencer. The receiver ran his route right over the middle of the field. |
| 2-4-SFO29 (4Q: 00:03) Donovan Frassrand ran inside the left guard for 4 yards. Tackled by S Mike Doss, assisted by DE Jim Ellison. Key block delivered by Dylan Gandy. PENALTY: San Francisco was called for Offsides. |
| 1-10-SFO24 (4Q: 00:03) Peyton Manning pass fell incomplete, intended for WR Steve Smith. DE Levon Dole simply tossed Ryan Lilja aside to reach the quarterback and hurry the throw. |
| Final Score: San Francisco 49ers 31, Indianapolis Colts 6 |